Telomir Prescription drugs Lead Drug Candidate Inhibits Tumor Development In Aggressive Prostate Most cancers Cells, Animal Examine Exhibits – Telomir Prescription drugs (NASDAQ:TELO)

On Wednesday, Telomir Prescription drugs, Inc. TELO revealed preclinical findings demonstrating that Telomir-1 reduces tumor dimension by roughly 50% in a prostate most cancers animal mannequin with aggressive most cancers cells.

The corporate says that Telomir-1 actively suppresses most cancers progress and protects towards chemotherapy-induced toxicity and mortality when mixed with Paclitaxel—a broadly used chemotherapy however typically related to extreme toxicity and uncomfortable side effects.

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Paclitaxel and different chemotherapy brokers induce toxicity largely by means of oxidative stress, which leads to extreme injury to wholesome cells and contributes to extreme uncomfortable side effects.

The corporate says that Telomir-1 can reverse oxidative stress by means of its metallic ion-regulatory actions, which can be answerable for eliminating chemotherapy-induced toxicity on this research.

“There has lengthy been a debate about whether or not telomere elongation may gasoline most cancers progress, however our findings present compelling proof that Telomir-1 does extra than simply lengthen telomeres—it actively suppresses tumor improvement…We’re seeing a drug that extends mobile well being whereas concurrently defending towards the very toxicity that usually limits therapy success,” stated Dr. Angel, Chief Scientific Advisor at Telomir.

Along with oncology, ongoing research are evaluating Telomir-1 in age-related ailments corresponding to age-related macular degeneration (AMD) and Wilson’s illness, a uncommon orphan dysfunction affecting copper metabolism.

The corporate is prioritizing the quickest pathway to medical trials and goals to submit its Investigational New Drug (IND) software by year-end.

In December, Telomir Prescription drugs introduced preclinical findings highlighting the copper-binding potential of Telomir-1 as a possible therapy for Wilson’s illness and associated issues.

The compound displays a binding affinity for copper ions, enabling exact regulation of copper metabolism and interacting with important ions corresponding to copper, iron, and zinc.

Value Motion: TELO inventory closed at $4.12 on Tuesday.

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