Tuesday, December 16, 2025

Big Information For Your Mind


However first . . .

For the reason that deal to reopen the federal government lasts solely till the top of January, don’t we get to do that once more in just a few weeks if the Republicans proceed to refuse to satisfy their constituents’ healthcare wants?

Within the meantime, we’ve reopened the federal government, staving off great hardship and financial loss . . .

. . . and proven that we’re those who need to feed poor youngsters and seniors and veterans on meals stamps . . . we’re those who need individuals to have reasonably priced well being care . . . they’re those who struggle this stuff, preferring tax cuts for billionaires and $40 billion for Argentina.

(Not that I’ve something in opposition to Argentina.)

In the event that they don’t come to their sense and relent, we simply resume the struggle in January, after they’ll once more want our votes to maintain the federal government open, having proven that we actually did give them each alternative to do the proper factor.

No?

Apologies prematurely if I’m being dense.  I used to be in laptop hell a lot of the day.



WITH LIBERTY AND JUSTICE FOR SOME

When you commit crimes for Trump or can bribe him adequately, you get a pardon.  When you oppose him, you get indicted.

Choose Mark L. Wolf lays it out so fantastically:

Why I Am Leaving the Federal Bench

It’s to cry.


Felon Freed by Trump Is Sentenced Once more, This Time to 27 Months

And (as you’ll see you probably have time to learn it) he’s hardly the one one.


The lack of knowledgeable, apolitical Justice Division strikes me as 10,000 instances extra essential than (say) who makes use of what toilet (does the federal authorities really want to become involved?) or Hunter Biden’s laptop computer (if there have been one thing of actual significance on it, wouldn’t the Trump regime have launched it by now?).



HURRICANE SEASON

Out of your wonderful fellow reader Bryan Norcross: no extra this yr; A.I. is now the very best predictor.



And now . . .

HUGE NEWS FOR YOUR BRAIN

Out of your wonderful fellow reader Jeff Zimman, Co-founder of BrainHQ mother or father Posit Science:


In case you missed it, I wished to share huge information from an NIH-funded research that has gotten an outpouring of press throughout the globe due to its big implications for getting older and dementia.

A neuroimaging crew at McGill discovered 10 weeks of every day BrainHQ coaching drove vital and substantial rejuvenation within the mind’s cholinergic system.

It’s the system that produces acetylcholine (the “concentrate” chemical) on the exact second it’s wanted.

We’ve identified for many years that this technique turns into more and more sluggish (downregulates) with regular getting older and plummets with pre-dementia and Alzheimer’s.

Actually, probably the most prescribed class of medicine for Alzheimer’s – cholinesterase inhibitors reminiscent of Aricept® – artificially flood the mind with acetylcholine to supply some transient aid, however don’t repair the underlying sluggishness in its manufacturing.

BrainHQ simply grew to become the first intervention of any variety proven to upregulate acetylcholine manufacturing.

The upregulation from 10 weeks of BrainHQ coaching at half-hour per day was about equal to the quantity a median older grownup downregulates over a decade. And the acquire continued 3 months after the coaching ended.

The management group did attentionally demanding on-line video games (like solitaire and sweet crush) for an equal period of time and confirmed no enchancment.

As famous by the researchers, WHAT you do issues — simply staying mentally lively isn’t sufficient.

The research offers a bio-chemical clarification of how BrainHQ rewires the mind and why BrainHQ, uniquely, has gotten the outcomes seen throughout a whole bunch of research. The implications for getting older, pre-dementia and Alzheimer’s are compelling, and a brand new NIH grant has been awarded to do an analogous research in MCI (pre-dementia). Many different situations are related to deficiencies in mind chemical compounds which BrainHQ can be designed to upregulate, suggesting a novel pathway for remedy.

I imagine historians will view this research as pivotal within the improvement of interventions to handle quite a few well being situations and likewise to assist us all with improved peak efficiency [e.g., Tom Brady].

This text was initially printed on November eleventh, 2025 on andrewtobias.com, syndicated with permission.

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